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Amedeo Caflisch

5 results in Authors: Amedeo Caflisch

Biological and Medicinal Chemistry

Exploring the binding pathway of novel non-peptidomimetic plasmepsin V inhibitors

Raitis Bobrovs, Laura Drunka, Iveta Kaņepe, Aigars Jirgensons, Amedeo Caflisch, Matteo Salvalaglio, Kristaps Jaudzems

Version 1 posted 26 May 2023

197

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Biological and Medicinal Chemistry

Structure-based design of a potent and selective YTHDC1 ligand

František Zálešák, Francesco Nai, Rajiv K. Bedi, Yaozong Li, Marcin Herok, Elena Bochenkova, Francesco Errani, Amedeo Caflisch

Version 1 posted 29 November 2023

340

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Biological and Medicinal Chemistry

PROTAC degraders of the METTL3-14 m6A-RNA methyltransferase

Francesco Errani, Annalisa Invernizzi, Marcin Herok, Elena Bochenkova, Fiona Stamm, Ivan Corbeski, Valeria Romanucci, Giovanni Di Fabio, František Zálešák, Amedeo Caflisch

Version 2 posted 06 February 2024

595

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Biological and Medicinal Chemistry

Structure-based Design of CBP/EP300 Degraders: When Coopera-tivity Overcomes Affinity

Ivan Cheng-Sanchez, Katherine Gosselé, Leonardo Palaferri, Eleen Laul, Gionata Riccabella, Rajiv Bedi, Yaozong Li, Anna Müller, Amedeo Caflisch, Cristina Nevado

Version 1 posted 26 March 2024

216

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Biological and Medicinal Chemistry

Development of a novel class of CBP/EP300 bromodomain inhibitors which block TNF-α induced NFκB signaling

Katherine Gosselé, Irene Latino, Eleen Laul, Mariia Kirillova, Vlad Pascanu, Emanuele Carloni, Rajiv Bedi, Amedeo Caflisch, Santiago Gonzalez, Cristina Nevado

Version 1 posted 26 March 2024

161

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