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Biological and Medicinal Chemistry

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Organic Chemistry

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Alicia Porro

3 results in Authors: Alicia Porro

Organic Chemistry

Contilisant+Belinostat hybrids, as new multi-target-directed polyfunctionalized indole derivatives able to inhibit histone deacetylase/cholinesterase/monoamine oxidase enzymes, and modulate histamine 3/sigma 1/5-HT6/dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

Mireia Toledano-Pinedo, Alicia Porro, Saray Macaulet, Pedro Almendros, Isabel Iriepa, M. Mercedes Rodríguez-Fernández, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu, José Marco-Contelles

Version 1 posted 03 August 2023

216

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Biological and Medicinal Chemistry

Contilisant+Tubastatin A hybrids, as new multi-target-directed polyfunctionalized indole derivatives able to inhibit histone deacetylase/cholinesterase/monoamine oxidase enzymes, and modulate histamine 3/sigma 1/5-HT6/dopamine 3 receptors for the treatment of cancer

José Luis Marco-Contelles, Mireia Toledano-Pinedo, Fernando Romero, Abdelouahid Samadi, Alicia Porro, Pedro Almendros, Isabel I Iriepa, M. Mercedes Rodríguez-Fernández, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu

Version 1 posted 01 September 2023

165

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Biological and Medicinal Chemistry

Contilistat, a new polyfunctionalized histone deacetylase inhibitor, showing potential capacity to inhibit cholinesterase/monoamine oxidase enzymes, and modulate histamine 3, sigma 1, 5-HT6 and dopamine 3 receptors for the treatment of cancer and neurodegenerative diseases

José Marco-Contelles, Daniel Diez-Iriepa, Mireia Toledano-Pinedo, Alicia Porro, Pedro Almendros, M. Mercedes Rodríguez-Fernández,, Abdelouahid Samadi, Isabel Iriepa, Francisco López-Muñoz, Aizpea Artetxe-Zurutuza, Ander Matheu

Version 1 posted 12 May 2023

250

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