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Biological and Medicinal Chemistry

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Organic Chemistry

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Alexis Richaud

5 results in Authors: Alexis Richaud

Biological and Medicinal Chemistry

Bent to Bind: Exploiting the Programmed Cell Death-1 (PD-1) Receptor Plasticity to Design Pembrolizumab H3 Loop Mimics

Mehdi Zaghouani, Guangkuan zhao, Alexis Richaud, Medhi Wangpaichitr, Niramol Savaraj, Stephane Roche

Version 1 posted 26 April 2021

458

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2

Citations

Organic Chemistry

Folding in Place: Design of β-Strap Motifs to Stabilize the Folding of Hairpins with Long Loops

Alexis Richaud, Guangkuan zhao, Stephane Roche, Samir Hobloss

Version 2 posted 03 February 2021

577

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Organic Chemistry

Structure-Property Relationship Study of N-(Hydroxy)Peptides for the Design of Self-Assembled Parallel β-Sheets.

Alexis Richaud, Stephane Roche

Version 1 posted 17 June 2020

444

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1

Citations

Organic Chemistry

De Novo Synthesis and Structural Elucidation of CDR-H3 Loop Mimics

Stephane Roche, Guangkuan Zhao, Alexis Richaud, Thomas Williamson, Michael Feig

Version 1 posted 28 May 2024

47

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Biological and Medicinal Chemistry

A Platform of ADAPTive Scaffolds: Development of CDR-H3 -Hairpin Mimics into Covalent Inhibitors of the PD1/PDL1 Immune Checkpoint.

Sarah Naylon, Alexis Richaud, Guangkuan Zhao, Linda Bui, Craig Dufresne, Chunjing Wu, Medhi Wangpaichitr, Niramol Savaraj, Stephane Roche

Version 1 posted 31 May 2024

85

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