The Intersection of Artificial Intelligence, Automation, and CRISPR-Cas9 in the Design of Universal Pandemic Vaccines

The creation of a universal vaccine is critical in the face of continually mutating viral infections. This work investigates the use of CRISPR-Cas9 technology for artificial intelligence and automation based manipulation of viral antigen expression in order to improve the efficacy and adaptability of vaccination candidates. This approach uses CRISPR-Cas9's accuracy in gene editing to systematically change viral antigens in order to find optimal configurations that elicit strong immune responses. The modern method combines high-throughput screening and analytics to accelerate the identification of effective antigenic targets across several virus strains. The findings show that targeted manipulation of viral antigens can greatly improve immunogenicity, paving the way for adaptable vaccination platforms capable of treating a wide range of viral diseases. This review emphasizes the promise of CRISPR-Cas9 artificial intelligence based automation as a transformational tool in universal pandemic vaccine development.