Isomeric and Tautomeric Structure of Amino Imino 5H-pyrrolo[3,4-b]pyridine Derivatives Revisited

15 May 2025, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

The interaction of pyridine-2,3-dicarbonitrile with aliphatic and aromatic primary amines has been carried out. The study of the structure of the products by means of 1H, 13C, 1D NOESY, 1H-15N HMBC experiments has shown that the reaction with aromatic amines proceeds regioselectively with the formation of 5H-pyrrolo[3,4-b]pyridine derivatives.

Keywords

pyridine-2
3-dicarbonitrile
5H-pyrrolo[3
4-b]pyridine
ring closure
regioisomerism
tautomerism

Supplementary materials

Title
Description
Actions
Title
1H 13C 1D NOESY 1H 15N HMBC of compounds 3 to 6
Description
A supplementary information file, containing images 1H, 13C, 1D NOESY, 1H-15N HMBC of compounds 3-6.
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