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Detection of Western Diamondback Rattlesnake (C. atrox) venom using Glycopolymer Functionalised Gold Nanoparticles

02 December 2024, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Every 5 minutes, 50 people are bitten by a snake worldwide, four will be permanently disabled and one will die.1,2 Most approaches to treating and diagnosing snake envenomation rely on antibody-based solutions. Here, we present a proof-of-concept for a glycan-based UV-vis assay to detect Crotalus atrox (C. atrox) venom versus model proteins and Indian Cobra (Naja naja, N. naja) venom.

Keywords

Snake
polymer
glycan
nanoparticle
venom

Supplementary materials

Title
Description
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Title
Supplementary Information for Detection of Western Diamondback Rattlesnake (C. atrox) venom using Glycopolymer Functionalised Gold Nanoparticles
Description
Supplementary Information for Detection of Western Diamondback Rattlesnake (C. atrox) venom using Glycopolymer Functionalised Gold Nanoparticles Including syntheses, UV-vis, BLI, XPS and other analytical methods
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Version History

Dec 02, 2024 Version 1

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License

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The content is available under CC BY NC 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-gx2q5
D O I: 10.26434/chemrxiv-2024-gx2q5 [opens in a new tab]

Funding

Leverhulme Trust
ECF-2023-497
Engineering and Physical Sciences Research Council
EP/X525844/1
Royal Society of Chemistry
U24-3487489279

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) declare that they have sought and gained approval from the relevant ethics committee/IRB for this research and its publication.

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