Chemistry of Scorpion Venom and its Medicinal Potential

22 November 2024, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Scorpion venom comprises a unique mix of peptides, proteins, enzymes, and other compounds, showing great medical potential. This review examines its chemical composition, categorising toxins into groups like α-toxins, β- toxins, potassium channel toxins (KTxs), calcins, and antimicrobial peptides, each with distinct pharmacological effects. It also highlights potential therapeutic applications in cancer treatment and antimicrobial therapies. While using scorpion venom for medical purposes is promising, challenges such as toxicity and non-selectivity toward healthy cells remain. Continued research is crucial to fully harness its therapeutic potential and address these issues for innovative treatment developments.

Keywords

Toxins
Enzymes
Antimicrobial Peptides
Structure-Activity Relationship
Pre-Clinical
Anti-Cancer
Anti-Microbial

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