Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Batch and continuous synthesis of 5,5-diphenylhydantoin, an active pharmaceutical ingredient

16 October 2024, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A teaching laboratory protocol was developed for the implementation of an ultrasound-assisted continuous-flow synthesis of 5,5-diphenylhydantoin, a drug used for epilepsy and tonic-clonic seizures. This methodology allowed students to understand concepts of green chemistry, ultrasound irradiation, continuous flow chemistry and drug synthesis.

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Oct 16, 2024 Version 1

Metrics

166
110
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-rrp4p
D O I: 10.26434/chemrxiv-2024-rrp4p [opens in a new tab]

Funding

Fundação para a Ciência e Tecnologia (FCT)
2022.08559.PTDC

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share