Energy transfer mediated alkoxy radical generation: the construction of 1,6-linkage using bifunctional oxime esters

The generation of long-chain alkoxy radicals via visible light-induced energy transfer (EnT) has been accomplished through the design of a new class of bifunctional oxime esters derived from iminophenylacetic acid. The 1,5-hydrogen atom abstraction (HAT) of the alkoxy radicals, followed by alkylamination of alkenes, enables the construction of a 1,6-linkage across a double bond to achieve the valuable 1,6-amino alcohols.