Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Catalytic coupling of 1,4-benzenedimethanol with ethanol for alcohol upgradation

26 August 2024, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

We report here a catalytic method to upgrade 1,4-benzenedimethanol to 3-(4-(hydroxymethyl)phenyl)propan-1-ol via coupling of 1,4-benzenedimethanol with ethanol using a ruthenium catalyst. Through systematic optimization of catalytic conditions, a high TON of 400,000 has been achieved. Based on previous studies and those reported herein, we suggest that the reaction proceeds via a hydrogen-borrowing mechanism in a Guerbet-style process.

Keywords

ruthenium
guerbet coupling

Supplementary materials

Title
Description
Actions
Title
Supporting information
Description
Supporting information file contains details of catalytic experiments.
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Aug 26, 2024 Version 1

Metrics

230
148
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-qd9kk
D O I: 10.26434/chemrxiv-2024-qd9kk [opens in a new tab]

Funding

Engineering and Physical Sciences Research Council
EP/Y005449/1

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) declare that they have sought and gained approval from the relevant ethics committee/IRB for this research and its publication.

Share