A roadmap towards the synthesis of Life

Dear authors of the prepublished preprint titled “A roadmap towards the synthesis of Life”, We appreciate your interest in identifying and laboratory reproducing the way used by Nature to synthesize simplest living entities. Meanwhile, the realistic way, which had led to the chemical synthesis of living entities from minerals under natural conditions, and the possibilities of realization of such a way under laboratory conditions were studied by us for more than 25 years. The chemical, thermodynamic, climatic, kinetic, and other characteristics of the roadmap used by Nature for synthesizing living entities and the peculiarities of such a roadmap capable of leading to the similar goal in a laboratory are considered by us in 15 peer-reviewed papers, presented in tens of lectures and reports, and generalized in the fundamental review paper: Kadyshevich Е.A. and Ostrovskii V.E., “From minerals to simplest living matter: Life Origination Hydrate Theory”, Acta Biotheoretica, 2023, 71, article 13 (pp. 1–67). By now, more than 2 800 inquisitive researchers downloaded this review paper from the journal site by the address https://doi.org/10.1007/s10441-023-09463-9 . We have a great number of complimentary reviews. The roadmaps are prompted to us by the Natural phenomena with no so-called models. These roadmaps are unique and no other ones exist. P.S. It would be great if you put into practice your interest in the problem of living matter origination by undertaking an experimental test of the Life Origination Hydrate Theory. The successful completion of this test could be the first step towards industrial synthesis of food from minerals, i.e., towards execution of the work that is done by plants. Sincerely, Dr. Victor E. Ostrovskii, Dr. Elena A. Kadyshevich.