Automation in Electrifying Flow Organic Synthesis

The automated chemicals flow in organic electrochemistry will accelerate the scale-up process. In traditional flow electrochemistry, the reaction parameters (concentration, current density, flow rate, temperature, pressure) can be precisely adjusted. However, control over these parameters in the automated electrochemical flow system will be innovative. Multi- objective algorithms that link hardware and digital chemical operations on software can establish the autonomous system for flow electro-organic reactions. Electrochemical transformations are controlled by the application of electrical current, so the chemical process in an electrochemical microreactor can be organised and started or stopped via computer- controlled power supply. Such control over chemical transformations is not possible in conventional chemical reactions. Due to advantage of this unique feature of electrochemical process, new methods for acquisition of real-time reaction data are possible with the help of online analysis and self-optimising machine learning algorithms. Herein, we build our opinions and describe the perspective of automation in flow organic electrochemistry.