Molecular Glues & Bifunctional Compounds: Therapeutic Modalities Based on Induced Proximity

03 April 2024, Version 2
This content is a preprint and has not undergone peer review at the time of posting.


This Perspective explores molecular glues and bifunctional compounds – proximity-inducing compounds – and offers a framework to understand and exploit their similarity to hot spots, missense mutations, and posttranslational modifications (PTMs).


Molecular Glues
Chemical inducers of proximity


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