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Abstract
In protein-RNA complexes, UVC crosslinks proteins predominantly to uracil. Concrete evidence for other UVC-crosslinked RNA bases is lacking. Here, I elucidate mass spectrometric signatures of UVC-crosslinked guanine, cytidine, and methyladenine. This can help us capture the native protein-RNA interactions in more detail.
Supplementary weblinks
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Github repository
Description
Fragpipe workflows, analysis results, protein sequence/annotation resources, and the custom Python codes used in this study have been deposited to the GitHub repository.
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