Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Lipase enzymes for sustainable synthesis of chiral active pharmaceutical ingredients (API) and key starting materials

18 January 2024, Version 1
Review
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Biocatalysis is considered as a green and sustainable process for synthesis of chiral organic building blocks and active pharmaceutical ingredients (API). Lipase catalysed kinetic and kinetic dynamic resolution process is frequently used for in API or KSM synthesis. This review describes the reported synthesis of chiral API/KSM molecules using lipase enzyme, since last 10 years.

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Jan 18, 2024 Version 1

Metrics

526
321
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-km1k1
D O I: 10.26434/chemrxiv-2024-km1k1 [opens in a new tab]

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share