![Author ORCID: We display the ORCID iD icon alongside authors names on our website to acknowledge that the ORCiD has been authenticated when entered by the user. To view the users ORCiD record click the icon. [opens in a new tab]](https://chemrxiv.org/engage/assets/public/chemrxiv/images/logos/orcid.png)
Abstract
Herein, we describe a nickel-catalyzed reductive difluoromethylation reaction of alkene using inexpensive and easy-to-handle DFAA/pyridine N-oxide reagent system. A variety of C(sp3)-CF2H containing compounds were prepared through a hydrodifluoromethylation process with good efficiency under mild conditions. In addition, various gem-difluoroalkenes bearing CF2H or 1o, 2o, 3o alkyl group were synthesized from trifluoromethyl alkenes via a defluorination process using this new established approach.
Supplementary materials
Title
Supplementary Information
Description
The General Information, Preparation of Substrates, Optimization of Reaction Conditions, NMR date and etc. are described in this file
Actions
