Ring-Walking Mediated by Ni–Ni Species as a Vehicle for Enabling Dis-tal C(sp2)–H Functionalization of Aryl Pivalates

08 November 2023, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Herein, we report the utilization of Ni-Ni species as a manifold for enabling a “ring-walking” event by a dynamic translocation of the metal center over the arene backbone. Experimental and computational studies support a translocation occurring via a 1,2-hydride shift. The synthetic applicability of the method is illustrated in a series of C–C bond for-mations that occur at distal C(sp2)–H sites of sim-ple aryl pivalates


C-H functionalization
C-O electrophile
remote functionalization

Supplementary materials

Supporting information
Supporting information with the synthesis of the complexes and detailed experiments


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