Abstract
A biphenyl derivative in which two benzene rings are strapped with two chains is prepared. The synthesized product shows molecular asymmetry, which was confirmed by HPLC analysis with chiral column and named as winding vine-shaped biphenyl. The synthesis of such vine shaped molecule was performed by ring-closing metathesis or alternatively by annulation with nosylated ethylenediamine. The structure of the obtained product was confirmed by X-ray crystallographic analysis. The absolute configuration of the molecular asymmetry was assigned after leading to the corresponding camphor sulfonamide through denosylation and re-amidation process.
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CCDC 2291758 (1b), 2291769 (8b), and 2291778 (9b) contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing [email protected], or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: + 44 1223 336033.
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