Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Fe-Electrocatalytic Deoxygenative Giese Reaction

29 September 2023, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

A redox-neutral Fe-electrocatalytic deoxygenative Giese reaction is reported. Hydroxyl groups are among the most abundant functional groups. The advancement of efficient conversion reactions holds significant importance in medicinal and process chemistry. In this report, we present a redox-neutral Giese reaction via anodic oxidation to generate phosphonium ions and cathodic reduction to yield low-valent Fe catalysts. This reaction constitutes a ground-breaking account of a redox-neutral reaction utilizing Fe-catalyst and electrochemistry. It will facilitate the exploration of diverse novel reactions employing this redox cycle in the future.

Keywords

electrochemistry
Fe-catalyst
Deoxygenative Giese Reaction

Supplementary materials

Title
Description
Actions
Title
Supporting Information
Description
Experimental Procedures and Characterization of Compounds
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Sep 29, 2023 Version 1

Metrics

2,277
1,470
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2023-xpc2f
D O I: 10.26434/chemrxiv-2023-xpc2f [opens in a new tab]

Funding

HKUST start-up funds
Project No. R9820
AMED and the New York Academy of Sciences
Interstellar Initiative Early Career Program

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share