Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters

20 September 2023, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Contemporary materials discovery requires intricate sequences of synthesis, formulation and characterization that often span multiple locations with specialized expertise or instrumentation. To accelerate these workflows, we present a cloud-based strategy that enables delocalized and asynchronous design–make–test–analyze cycles. We showcase this approach through the exploration of molecular gain materials for organic solid-state lasers as a frontier application in molecular optoelectronics. Distributed robotic synthesis and in-line property characterization, orchestrated by a cloud-based AI experiment planner, resulted in the discovery of 21 new state-of-the-art materials. Automated gram-scale synthesis ultimately allowed for the verification of best-in-class stimulated emission in a thin-film device. Demonstrating the asynchronous integration of five laboratories across the globe, this workflow provides a blueprint for delocalizing – and democratizing – scientific discovery.


Self-Driving Laboratory
Organic Laser
Building Block
Bayesian Optimization

Supplementary materials

Supplementary Information
Experimental procedures, compound characterization data, computational workflows.

Supplementary weblinks


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