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Are unlicensed feline coronavirus antiviral compounds GS-441524 and GC376 what they claim to be? A qualitative and quantitative analysis.

14 September 2023, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Feline infectious peritonitis (FIP) caused by feline coronavirus was, until recently, considered both fatal and untreatable. Experimental antivirals such as GS-441524 and GC376 can be obtained off-label through crowdsourced internet groups and have been used by pet owners to treat FIP. We describe analysis and characterization of unregulated batches of both GS-441524 and GC376

Keywords

Feline Infectious Peritonitis
FIP
GS-441524
GC376
Molnupiravir
EIDD
Feline Coronavirus
Remdesivir

Supplementary materials

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Are unlicensed feline coronavirus antiviral compounds GS-441524 and GC376 what they claim to be? A qualitative and quantitative analysis supplemental information.
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Version History

Sep 14, 2023 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2023-jjwj7
D O I: 10.26434/chemrxiv-2023-jjwj7 [opens in a new tab]

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

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