Qualitative monitoring of proto-peptide condensation by differential FTIR spectroscopy

04 September 2023, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Condensation processes such as wet-dry cycling are thought to have played significant roles in the emergence of proto-peptides. Here, we describe a simple and low-cost method, differential Fourier transform infrared (FTIR) spectroscopy, for qualitative analysis of peptide condensation products in model primordial reactions. This method is optimized for depsipeptides and is used to investigate their polymerization in the presence of extraterrestrial dust simulants.

Keywords

FTIR
wet-dry cycling
depsipeptides
prebiotic chemistry
astrobiology

Supplementary materials

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Description
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Supplemental Information
Description
FTIR and MALDI-TOF MS data.
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