Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Qualitative monitoring of proto-peptide condensation by differential FTIR spectroscopy

04 September 2023, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Condensation processes such as wet-dry cycling are thought to have played significant roles in the emergence of proto-peptides. Here, we describe a simple and low-cost method, differential Fourier transform infrared (FTIR) spectroscopy, for qualitative analysis of peptide condensation products in model primordial reactions. This method is optimized for depsipeptides and is used to investigate their polymerization in the presence of extraterrestrial dust simulants.

Keywords

FTIR
wet-dry cycling
depsipeptides
prebiotic chemistry
astrobiology

Supplementary materials

Title
Description
Actions
Title
Supplemental Information
Description
FTIR and MALDI-TOF MS data.
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Qualitative Monitoring of Proto-Peptide Condensation by Differential FTIR Spectroscopy [opens in a new tab]
Keon Rezaeerod, Hanna Heinzmann, Alexis V. Torrence, Jui Patel, Jay G. Forsythe journal article
ACS Earth and Space Chemistry
Online publication date: May 06, 2024

Version History

Sep 04, 2023 Version 1

Metrics

323
152
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2023-hlfmp
D O I: 10.26434/chemrxiv-2023-hlfmp [opens in a new tab]

Funding

NSF
CHE-1504217
NIH SC INBRE
P20GM103499-20
NASA SC EPSCoR

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share