A Conjoined Rectilinear Collision Cell and Pulsed Extraction Ion Trap with Auxiliary DC Electrodes.

25 August 2023, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Ion traps are routinely directly coupled to mass analyzers, where they serve to suitably cool and shape an ion population prior to pulsed extraction into the analyzer proper. Such devices benefit from high duty cycle and transmission but suffer slow ion processing times caused by compromise in the buffer gas pressure range that suitably dampens injected ion kinetic energy, without causing excessive scatter during extraction or within the analyzer. A rectilinear RF quadrupole ion trap has been characterized, conjoining a pressurized collision region with a pumped extraction region, and an unbroken RF interface for seamless ion transfer between them. Auxiliary electrodes mounted between the RF electrodes provide DC voltage gradients that serve to both guide ions through the device and position them at the extraction slot. The influence of the auxiliary DC upon the trapping RF field was measured, and suitable parameters defined. A mode of operation was developed that allowed parallel processing of ions in both regions, enabling a repetition rate of 200Hz when the device was coupled to a high-resolution accurate-mass analyzer.

Keywords

Mass Spectrometry
Ion Trap
Collision Cell
Orbitrap Astral
Astral Analyzer

Supplementary materials

Title
Description
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Title
Ion Processor Supplementary Results
Description
Additional images of the Ion Processor; further optimization to the mechanical design; measurement of intact carbonic anhy-drase MS and MS/MS; analysis of the pseudopotential well interference generated by auxiliary DC electrodes, and optimization of applied dynamic DCs (PDF)
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