An Extrusion Strategy for On-demand SF5Cl Gas Generation from a Commercial Disulfide

Herein, we report a novel methodology for the ex-situ generation of SF5Cl by employing 4,4′-dipyridyl disulfide as a safe commercial reagent obviating the need for lecture bottles. The method is applicable to certain SF5Cl-involving transformations using a two-chamber reactor. Moreover, easily applying SF5Cl in both polar and non-polar media is rendered feasible while avoiding the use of glovebox techniques. This report also suggests 1H-19F HOESY as a simple and fast stereochemistry indication for chloropentafluorosulfanylated olefins.