Abstract
We present a novel approach utilizing 19F-nuclear magnetic resonance (NMR) spectroscopy for serum amine profiling. Our method introduces a highly efficient and reliable technique for fluorine labeling of amine metabolites via Schiff base formation. By employing this fluorine labeling, we successfully achieve accurate identification and quantification of amine metabolites in human serums, providing valuable insights for metabolomics research.
Supplementary materials
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Supporting Information
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Experimental details and spectral data
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