Copper-Catalyzed Sulfimidations of Benzylic C(sp3)-H Bonds

In this study, we elucidate a novel strategy for benzylic C(sp3)-H activation, enabling the construction of C-S bonds through a copper-catalyzed sulfimidation process. Leveraging readily available methylarenes as substrates, our methodology offers an economically efficient and highly viable approach. The scalability of the reaction, its applicability to a broad range of substrates, and significant application value underscore its potential and transformative impact in the realm of synthetic organic chemistry.