Revealing the effects of three different antimicrobial agents on E. coli biofilms by using Soft-Probe Scanning Electrochemical Microscopy

This paper evaluated the use of Soft-Probe-SECM to study the effects of different antimicrobial agents and treatments on E. coli biofilms. The antimicrobial agents were sodium azide, silver nanoparticles, and a flashlight. The effects of these agents were monitored by measuring the change in biofilm properties, such as biofilm thickness, viability, and activity. The results showed that sodium azide and silver nanoparticles effectively killed E. coli biofilms. Sodium azide was more effective at killing the biofilm at short treatment times, while silver nanoparticles were more effective at killing the biofilm at longer treatment times. SECM is a valuable tool for studying the effects of antimicrobial agents on biofilms. SECM is a sensitive technique that can be used to monitor the change in biofilm properties in real-time. Additionally, SECM does not require any sample preparation, which makes it a convenient and efficient technique. The results of this study could be used to develop new strategies for treating E. coli biofilm infections. Overall, this study provides valuable insights into the use of SECM to study the effects of antimicrobial agents on E. coli biofilms. The results of this study could be used to develop new strategies for treating E. coli biofilm infections.