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Bicyclic Bioisosteres of Piperidine: Version 2.0

12 April 2023, Version 1

Abstract

1-Azaspiro[3.3]heptanes were synthesized, characterized, and validated biologically in vivo as a new generation of saturated piperidine bioisosteres.

Supplementary materials

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Version History

Apr 12, 2023 Version 1

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The content is available under CC BY NC 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2023-rpjld
D O I: 10.26434/chemrxiv-2023-rpjld [opens in a new tab]

Funding

European Research Council
101000893

Author’s competing interest statement

Authors of this work are employees of a chemical supplier Enamine.

Ethics

The author(s) declare that they have sought and gained approval from the relevant ethics committee/IRB for this research and its publication.

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