Nickel Catalyzed Cross Coupling of Aryl and Alkenyl Triflates with Alkyl Thiols



We report a nickel catalyzed C-S cross-coupling of aryl and alkenyl triflates with alkyl thiols. A variety of the corresponding thioethers were synthesized using an air-stable nickel precatalyst under mild reaction conditions with short reaction times. A broad substrate scope, including pharmaceutically relevant compounds, could be demonstrated.


Supplementary material

Supporting Information
Experimental and spectral data