Abstract
Several additives and solvent allow reversing the polymorphic outcome of solvent mediated phase transformation experiments and crystallization, as well as the apparent relative solubility of polymorphs of the antibacterial drug nitrofurantoin.
Supplementary materials
Title
Switching nitrofurantoin polymorphic outcome ESI
Description
Experimental details, Evaluation of relative stability of nitrofurantoin polymorphs, Crystal form outcome of crystallization, Nucleation induction times, Speciation in solution, Analysis of crystal structures and morphology of nitrofurantoin polymorphs, Characterization of α obtained in the crystallization from acetonitrile in presence of BIS-TRIS
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