Catalytic Olefin Transpositions Facilitated by Ruthenium N,N,N-Pincer Complexes

13 December 2022, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Previous reports with our N,N,N-pincer Ru hydride catalysts have shown their synthetic versatility in the ability to perform various transfer dehydrogenation reactions, deuterations, and (semi)-hydrogenations. In this report, we expand the reactivity of these complexes to encompass olefin transposition/isomerization via a chain-walking mechanism. Furthermore, we report several one-pot cascade reaction sequences derived from the products of the transposition reactions. The protocol occurs at room temperature achieving excellent yields, regioselectivity, and diastereoselectivity in short reaction times


metal hydride


Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.