Photosensitizer Free Visible Light Synthesis of Multifunctional Coumarins from Trans-hydroxy acrylates

29 November 2022, Version 2
This content is a preprint and has not undergone peer review at the time of posting.


A photosensitive and transition metal-free technique without inert gas shielding is reported for the facile synthesis of multifunctional coumarins. The current proce-dure avoids the inherent drawbacks of the previous coumarin production protocol in the presence of transition metal. The prominent aspects of the methodology also include the absence of photocatalyst, the absence of external additives including transition metals, and the employment of a straightforward precursor. Additionally, we went into great detail on the mechanistic investigation and utilization of multi-functional coumarins.


Visible Light
Photosensitiser Free

Supplementary materials

Photosensitizer Free visible Light Synthesis of multifunctional Coumarins from Trans-hydroxy acrylates
In summary, we have achieved the first visible-light-driven, photosensitizer free and transition metal-free technique without inert gas shielding is reported for the facile synthe-sis of multifunctional coumarins. The method is mild, op-erationally simple, tolerant of a number of functional groups and exhibit excellent scalability. We believe this methodology provides practitioners with an alternative tool that will permit the scrutiny of unexplored chemical space and find useful applications in organic synthesis.


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