Synthesis of γ-alkenylated δ-sultones via Brønsted base-catalyzed Michael addition-SuFEx click reaction of allyl ketones and ethenesulfonyl fluorides

A tandem annulation reaction of allyl ketones and ethenesulfonyl fluoride has been described. Under the catalysis of Brønsted base, vinyl ketones reacted with ethenesulfonyl fluoride through a cascade intermolecular Michael addition-intramolecular SuFEx process to afford γ-alkenylated δ-sultones in good to excellent reaction yields. In this reaction, no additional base was needed, and 4 Å Molecular sieves was used as efficient HF scavenger to restrict the neutralization and deactivation of the Brønsted base catalyst.