Basic principle of soft ionization mass spectrometry and development of ion source

18 October 2022, Version 2
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Since the discovery of soft ionization technology represented by electrospray, the basic principle of soft ionization technology - how analyte is charged remains an unsolved mystery. In this paper, the basic principle of soft ionization technology is discussed, some summarized basic physical and chemical principles are briefly described, and its application in the development of ion source is discussed.

Keywords

Electrospray
Soft ionization technology
Basic physical and chemical principles
Development of ion source

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