Basic principle of soft ionization mass spectrometry and development of ion source

jiehong luo

doi:10.26434/chemrxiv-2022-7sx1d-v2

Analytical Chemistry

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Basic principle of soft ionization mass spectrometry and development of ion source

18 October 2022, Version 2

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jiehong luo

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Abstract

Since the discovery of soft ionization technology represented by electrospray, the basic principle of soft ionization technology - how analyte is charged remains an unsolved mystery. In this paper, the basic principle of soft ionization technology is discussed, some summarized basic physical and chemical principles are briefly described, and its application in the development of ion source is discussed.

Keywords

Electrospray

Soft ionization technology

Basic physical and chemical principles

Development of ion source

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