Isocyanide Chemistry Enabled by Continuous Flow Technology

06 October 2022, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Isocyanides are valuable compounds for organic synthesis. However, the poor stability and distressing odour have often limited their widespread applications in common laboratory practice and industrial setting. Herein, a continuous flow approach to enable the synthesis, purification and in-line multicomponent reaction of isocyanides, is presented.

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