Abstract
This study reviewed the use of cyanoacetohydrazide as versatile precursor for synthesis of some heterocyclic compounds, as it contains five different functional groups ( cyano group, No. 1, active methylene group, No. 2, carbonyl group, No. 3, amido group, No. 4 and hydrazine group, No.5 ) The reviewed reactions were classified according to the active centers of cyanoacetohydrazide involved. Accordingly, they are divided into 12 classes in which heterocycles was obtained via the utility of the following functional groups: a - groups No. 1, 2, b - groups No. 1,5, c - groups No. 2, 3 , d - groups No. 2,4 , e - groups No. 2,5 , f- groups No. 3,5 , g- groups No. 4,5 , h- groups No. 1,2,5, i- groups No. 1,4,5, j- groups No. 2,4,5, k- groups No. 1,2,4,5, l-groups No. 2,3,4,5 .This review covers literature up to 2021.