Copper-based 2D Conductive Metal Organic Framework Thin Films for Ultrasensitive Detection of Perfluoroalkyls in Drinking Water

20 June 2022, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Perfluoroalkyls (PFAS) continue to emerge as a global health threat making their effective detection and capture extremely important. Though metal organic frameworks (MOF) have stood out as a promising class of porous materials for sensing PFAS, detection limits remain insufficient and fundamental understanding of detection mechanisms warrant further investigation. Here we show the use of a 2D conductive MOF film based on copper hexahydroxy triphenylene (Cu-HHTP) to fabricate a chemiresistive sensing device for detecting PFAS in drinking water. We further show ultrasensitive detection using electrochemical impedance spectroscopy. Owing to excellent electrostatic attractions and electrochemical interactions between the copper-based MOF and PFAS, the MOF-based sensor reported herein exhibits unprecedented affinity and sensitivity towards perfluorinated acids at concentrations as low as of 0.002 ng/L.


2D metal-organic frameworks
forever chemicals
bio-cumulative compounds
MOF thin-films
MOF-based sensors

Supplementary materials

Supporting figures and experimental details
Supporting figures and experimental details.


Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.