Non-Directed Pd-Catalyzed Electrooxidative Olefination of Arenes

09 June 2022, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


The Fujiwara-Moritani reaction is a powerful tool for the olefination of arenes by Pd-catalyzed C–H activation. However, the need for superstoichiometric amounts of toxic chemical oxidants makes the reaction unattractive from an environmental and atom-economical view. Herein, we report the first non-directed and regioselective olefination of simple arenes via an electrooxidative Fujiwara-Moritani reaction. The versatility of this operator-friendly approach was demonstrated by a broad substrate scope that includes arenes, heteroarenes and a variety of olefins. Electroanalytic studies suggest the involvement of a Pd(II)/Pd(IV) catalytic cycle via a Pd(III) intermediate.


C–H activation • Pd catalysis • olefination • synthetic electrochemistry • Pd(III) intermediate

Supplementary materials

Supplementary Information
Supporting information contains the experimental details in-cluding optimization details, crystal details, spectroelectro-chemical study, characterization data, 1H, 13C NMR spectra of all the isolated compounds.

Supplementary weblinks


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