Programmed ripening of nanoparticles using a DNA template

02 June 2022, Version 2
This content is a preprint and has not undergone peer review at the time of posting.


Nanoparticle (NP) ripening is a process where energetically favored larger particles grow at the expense of smaller ones: while important in NP synthesis, it is often difficult to control during NP applications. Here, we unveil a new Contact-dependent, Localized Galvanic Ripening (CLGR) mechanism that enables precise control of NP ripening in solution. As neighboring silver NPs on a DNA origami template grow homogeneously to the point of making contact, the subtle size-dependent electrochemical potential differences of the NPs promote one silver shell to erode and redeposit locally onto the adjacent NP, leading to asymmetric structures. The unique on/off control through NP contact in CLGR presents a strategy to program the erosion and growth of specific NPs in a construct, which we exploit to synthesize customized heterogeneous core-shell NP structures with pre-designed plasmonic properties. CLGR is an essential phenomenon to consider for future nanodevice and nanophotonics designs.


metal nanoparticles
DNA origami
silver transfer
nanoparticle ripening

Supplementary materials

Supplementary Information
Supplementary figures and tables, including all spectroscopic, imaging and microscopic characterisation.


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