Glycosylation and the global virome

Cassandra Pegg; Benjamin Schulz; Benjamin Neely; Gregory Albery; Colin Carlson

doi:10.26434/chemrxiv-2022-w8j7x-v2

Analytical Chemistry

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Glycosylation and the global virome

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Cassandra Pegg University of Queensland ,
Benjamin Schulz University of Queensland ,
Benjamin Neely National Institute of Standards and Technology ,
Gregory Albery Georgetown University ,
Colin Carlson Georgetown University

Abstract

The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation - and harnessing it for predictive science - could help close the molecular gap in zoonotic risk assessment.