Organic Chemistry

Vaping Cannabinoid Acetates Leads to Ketene Formation

Authors

Abstract

Delta-8 THC acetate is a relatively new psychoactive cannabis product that is available online and in vape shops across the US since it is currently unregulated. Because it contains a similar substructure to vitamin E acetate, which has been shown to form the poison gas ketene during vaping, we investigated potential ketene formation from delta-8 THC acetate, as well as other cannabinoids acetates, CBN acetate and CBD acetate, under vaping conditions. Ketene was consistently observed in vaped condensates from all three acetates as well as from a commercial delta-8 THC acetate product purchased online.

Content

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Supplementary material

Thumbnail image of SI for preprint upload 5 3.docx
Vaping Cannabinoid Acetates Leads to Ketene Formation
NMR spectra of vaped cannabinoid acetate condensate samples