Materials Chemistry

Polyester-Tethered Near-Infrared Fluorophores Confined in Colloidal Nanoparticles: Tunable Excitonic Coupling and Biomedical Applications

Authors

Abstract

Intricate assembly of multiple molecular chromophores assisted by protein scaffolds is essential in tuning the optical absorption and energy transfer in the light-harvesting complexes of the photosynthetic systems in nature. However, it remains a challenge to achieve such structural complexity and functionality in synthetic polymer-chromophore systems. Here we report a series of polyester-tethered pyrrolopyrrole cyanine derivatives and their colloidal nanoparticles dispersed in water, which show tunable J- or H-aggregation excitonic coupling and near-infrared fluorescence by precise control of the polymer chain lengths, composition, and temperature. Moreover, the optimal fluorescence or photothermal effect of the J-aggregates nanoparticles enables broad applications in fluorescence or photoacoustic bioimaging and phototherapy.

Content

Thumbnail image of PPCy-ChemRxiv.pdf

Supplementary material

Thumbnail image of J-aggregation-SI.pdf
Polyester-Tethered Near-Infrared Fluorophores Confined in Colloidal Nanoparticles: Tunable Excitonic Coupling and Biomedical Applications
The supplementary materials includes detailed experimental section and additional figures and tables.