Abstract
This perspective article reviews experimental and theoretical works where rare gas clusters and helium
nanodroplet are used as nanoreactor to investigate chemical dynamics in a solvent environment. A
historical perspective is presented first, then specific considerations on the mobility of reactants within
these reaction media. The dynamical response of pure clusters and nanodroplets to photoexcitation
is shortly reviewed before examining the role of the cluster (or nanodroplet) degrees of freedom on
the photodynamics of the guest atoms and molecules.