Tungsten-containing formate dehydrogenase from Methylorubrum extroquens AM1 (FoDH1) was investigated from structural biology and bioelectrochemistry. The electron transfer (ET) pathways were investigated by structural information, electrostatic interactions between the electrode and the enzyme, and the differences in the substrates. Two electrode-active sites and multiple ET pathways in FoDH1 were discovered.
Multiple electron transfer pathways of tungsten-containing formate dehydrogenase in direct electron transfer-type bioelectrocatalysis
Supporting information for the main manuscript. Experimental procedures, structural analysis, structural properties of FoDH, and electrochemistry of FoDH are described