Using Lifetime and Quenching Rate Constant to Determine Quencher Concentration

09 February 2022, Version 1
This content is a preprint and has not undergone peer review at the time of posting.


Excited state quenching is a key step in photochemical reactions that involve energy or electron transfer. High reaction quantum yields require sufficiently high concentrations of quencher to ensure efficient quenching. Determination of quencher concentrations is typically done through trial and error. Using kinetic modeling, however, a simple relationship was developed that predicts the concentration of quencher necessary to quench 90% of excited states, using only the photosensitizer lifetime and the rate constant for quenching as inputs. Comparison of predicted quencher concentrations and quencher concentrations used in photoredox reactions featuring acridinium-based photocatalysts reveals that the majority of reactions used quencher concentrations significantly below the predicted concentration. This suggests these reactions exhibit low quantum yields, requiring long reaction times and/or intense light sources.


Kinetic Modeling
Quantum Yield

Supplementary materials

Supplementary Information
Description of kinetic modeling procedure; impact of illumination intensity and simulation time on quantum yield; percent difference between modeled and predicted quantum yield; details for data in Figures 2 and 3


Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.