Conversion of carboxylic acids to amides under the action of tantalum(V) chloride

29 November 2021, Version 1
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

It was found that the reaction of aliphatic carboxylic acids with secondary amines under the action of tantalum (V) chloride leads to the selective formation of carboxamides. N,N-Diethyladamantane-1-carboxamide were synthesized with a yield of 73% as well.

Keywords

carboxylic acids
carboxamides
tantalum (V) chloride
secondary amines
N
N-Diethyladamantane-1-carboxamide

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