Cambridge Open Engage home
What is Cambridge Open Engage?
How to Submit
Browse
About
News [opens in a new tab]

Competitive Gold/Nickel Transmetalation

29 October 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Transmetalation is a key method for the construction of element-element bonds. Here, we disclose the reactivity of [NiII(Ar)(I)(diphosphine)] compounds with arylgold(I) transmetalating agents, which is directly relevant to cross-coupling catalysis. Both aryl-for-iodide and unexpected aryl-for-aryl transmetalation are witnessed. Despite the strong driving force expected for Au-I bond formation, aryl scrambling can occur during transmetalation and may complicate the outcomes of attempted catalytic cross-coupling reactions.

Keywords

Cross-Coupling
Gold
Nickel
Boron
Ligand Design
Density Functional Theory
Aryl
Ambiphilic Ligand

Supplementary materials

Title
Description
Actions
Title
Supporting Information
Description
Supporting Information associated with article.
Actions
Title
Crystallographic Information Files
Description
Crystallographic Information Files
Actions
Title
XYZ Coordinate Files
Description
XYZ Coordinate Files (DFT)
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Competitive gold/nickel transmetalation [opens in a new tab]
Mitchell J. Demchuk, Joseph A. Zurakowski, Brady J. H. Austen, David J. Nelson, Marcus W. Drover journal article
Chemical Communications , Volume 58, Issue 1
Online publication date: 2022

Version History

Oct 29, 2021 Version 1

Metrics

980
369
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2021-kszpg
D O I: 10.26434/chemrxiv-2021-kszpg [opens in a new tab]

Funding

Natural Sciences and Engineering Research Council of Canada
RGPIN-2020-04480

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) declare that they have sought and gained approval from the relevant ethics committee/IRB for this research and its publication.

Share