Aptamers for Detection and Diagnostics (ADD): Can mobile systems process optical data from aptamer sensors to identify molecules indicating presence of SARS-CoV-2 virus? Should healthcare explore aptamers as drugs for prevention as well as its use as adjuvants with antibodies and vaccines?

12 October 2021, Version 34
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

Proposed SARS-CoV-2 surveillance tool using a mobile app for non-invasive monitoring of humans and animals.

Engineering a biomedical device as a low-cost, non-invasive, detection, and diagnostic platform for surveillance of infections in humans, and animals. The system embraces the IoT “digital by design” metaphor by incorporating elements of connectivity, data sharing and (secure) information arbitrage. Using an array of aptamers to bind viral targets may help in detection, diagnostics, and potentially prevention in case of SARS-CoV-2. The ADD tool may become part of a broader platform approach.

Keywords

SARS-CoV-2
COVID-19
Aptamers
Mobile app
HoloLens
Machine Learning
oligonucleotide detection method
diagnostics applications

Supplementary weblinks

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