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Synthetic Studies of Maleimide Derivatives for Bioconjugates Polymers by RAFT polymerization.

21 September 2021, Version 1
Working Paper
This content is a preprint and has not undergone peer review at the time of posting.

Abstract

An efficient method for the synthesis of maleimides derivatives in toluene in presence of PTSA is described. The method features a broad substrate scope of utility in both simple and complex setting and provide access to valuable derivatives without any column chromatography purification is described.

Keywords

maleimides
Bismaleimides
conjugates
RAFT polymer
PTSA
Condensation.

Supplementary materials

Title
Description
Actions
Title
mmaleimide experimental part
Description
Maleimide experimental part includes experimental details of amidic acid and imides with all spectral values characterization.
Actions
Title
Maleimide spectral part
Description
Maleimide spectral part includes data of products and starting materials .
Actions

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Version History

Sep 21, 2021 Version 1

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License

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BY
The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2021-xhq0n
D O I: 10.26434/chemrxiv-2021-xhq0n [opens in a new tab]

Funding

S.R.G is thankful to Prof. Brent Sumerlin, SMU for supporting in the form of post-doctoral associate fellowship during January-2006 to December-2007 and allowing to work on this work.

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) declare that they have sought and gained approval from the relevant ethics committee/IRB for this research and its publication.

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