Inorganic Chemistry

Reconciling Imbalanced Transition State Effects with Nonadiabatic CPET Reactions

Authors

Abstract

Recently there have been several experimental demonstrations of how concerted proton electron transfer (CPET) reaction rates are affected by off-main-diagonal energies, namely the stepwise thermodynamic parameters ΔG°PT and ΔG°ET. Semi-classical structure-activity relationships have been invoked to rationalize these asynchronous linear free energy relation-ships despite the widely acknowledged importance of quantum effects such as nonadiabaticity and tunneling in CPET reactions. Here we report variable temperature kinetic isotope effect data for the asynchronous reactivity of a terminal Co-oxo complex with C–H bonds and find evidence of substantial quantum tunneling which is inconsistent with semi-classical models even when including tunneling corrections. This indicates substantial nonadiabatic tunneling in the CPET reactivity of this Co-oxo complex and further motivates the need for a quantum mechanical justification for the in-fluence of ΔG°PT and ΔG°ET on reactivity. To reconcile this dichotomy, we include ΔG°PT and ΔG°ET in nonadiabatic models of CPET by having them influence the anharmonicity and depth of the proton potential energy surfaces, which we approximate as Morse potentials. With this model we independently reproduce the dominant trend with ΔG°PT + ΔG°ET as well as the subtle effect of ΔG°PT − ΔG°ET (or η) in a nonadiabatic framework. The primary route through which these off-diagonal energies influence rates is through vibronic coupling. Our results reconcile predictions from semiclassical transition state theory with models that treat proton transfer quantum mechanically in CPET reactivity and suggest that similar treatments may be possible for other nonadiabatic processes.

Content

Thumbnail image of Manuscript.pdf

Supplementary material

Thumbnail image of SI.pdf
Supporting Information
Additional spectra, data, and simulations.
Thumbnail image of TOC.tif
TOC Image
TOC Image